Jejum intermitente não é só para perda de peso: quais outras aplicações clínicas?

Atualmente está muito em voga a palavra jejum intermitente (JI). Profissionais da área de saúde, blogueiros,  influencers e curiosos fornecem informações diárias sobre essa nova prática de emagrecimento. Mas a prática do jejum intermitente vai muito além da estética e perda de peso. Estudos animais e clínicos vem demonstrando ao longo do tempo que o JI é muito mais que uma moda de dieta,mas sim uma prática científica que promove saúde e bem estar físico com o tempo.

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Hyper-Long Telomeres Give Non-Genetically Modified Mice Longer, Healthier Lives

Scientists at the Spanish National Cancer Research Centre (CNIO) generated the first mice that have super-long telomeres in every one of their body cells. Studies with the animals showed that in comparison with mice that have normal length telomeres, the hyper-long telomere animals lived on average nearly 13% longer, were leaner with less white fat tissue, and had better metabolic health. The researchers generated the mice from embryonic stem (ES) cells that carry the hyper-long telomeric repeats capping the ends of their chromosomes. The most relevant achievement for the scientists is that for the first time longevity was significantly increased without any genetic modification. “This finding supports the idea that, when it comes to determining longevity, genes are not the only thing to consider,” commented research lead Maria Blasco, PhD, head of the CNIO Telomeres and Telomerase Group. “There is a margin for extending life without altering the genes.”

Blasco and colleagues published their findings in Nature Communications, in a paper titled, “Mice with hyper-long telomeres show less metabolic aging and longer lifespans.”

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Creatine Arms T Cells for the Battle against Cancer

UCLA scientists report that creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, serves as a molecular battery for immune cells by storing and distributing energy to power their fight against cancer. They say their study, conducted in mice and published in the Journal of Experimental Medicine, is the first to show that creatine uptake is critical to the anti-tumor activities of CD8 T cells (aka killer T cells). The researchers also found that creatine supplementation can improve the efficacy of existing immunotherapies.

“Because oral creatine supplements have been broadly utilized by bodybuilders and athletes for the past three decades, existing data suggest they are likely safe when taken at appropriate doses,” said Lili Yang, PhD, a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA and the study’s senior author. “This could provide a clear and expedient path forward for the use of creatine supplementation to enhance existing cancer immunotherapies.”

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Cómo las Terapias Metabólicas Previenen y Tratan las Enfermedades Crónicas

HISTORIA EN BREVE

  • Cada vez más pruebas demuestran que enfermedades como el cáncer y Alzheimer son enfermedades metabólicas, lo que significa que las puede prevenir, tratarse y recuperarse de ellas, tal como ocurre con otros padecimientos metabólicos como la diabetes tipo 2 y las enfermedades cardíacas
  • Ahora varios expertos e investigadores están convencidos de que la respuesta a las epidemias de cáncer y Alzheimer que van en aumento, es una dieta cetogénica y otro soporte metabólico, como el ayuno, tratamientos con oxígeno hiperbárico y la suplementación alimenticia
  • Durante el ayuno o la cetosis, el cerebro hace una transición para emplear cuerpos cetónicos derivados de las grasas alimenticias como su combustible principal, y las cetonas tienen poderosos efectos neuroprotectores y mejoran la función cerebral
  • Las células sanas tienen la flexibilidad metabólica para usar tanto glucosa como cetonas (que se obtienen de los alimentos, a partir de carbohidratos y grasas saludables, respectivamente), mientras que las células cancerosas no pueden usar cetonas como combustible ya que tienen dañadas sus mitocondrias
  • La cetosis nutricional previene y combate el cáncer al optimizar la función mitocondrial, disminuir los niveles de la glucosa e insulina en la sangre, aumentar la oxigenación tisular, reducir la generación de radicales libres, regular negativamente los oncogenes y positivamente los genes supresores tumorales

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Hyperbaric oxygen therapy for Alzheimer’s disease

 

 

 

 

 

 

The authors report the case of a 58-year-old female who had experienced five years of cognitive decline, which began accelerating rapidly. Single photon emission computed tomography (SPECT) suggested Alzheimer’s disease. The diagnosis was confirmed by 18Fluorodeoxyglucose (18FDG) positron emission tomography (PET) brain imaging, which revealed global and typical metabolic deficits in Alzheimer’s.

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How to Detox Heavy Metals to Help End Exhaustion and Chronic Fatigue

 

 

 

 

 

By Dr. Mercola

Detoxification is an important aspect of optimal health, but can be quite confusing, not to mention risky if done incorrectly. Wendy Myers, a functional diagnostic nutritionist, founder of MyersDetox.com and author of “Limitless Energy: How to Detox Toxic Metals to End Exhaustion and Chronic Fatigue,” is a treasure trove of information on this topic.

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