Scientists discover ‘why stress turns hair white’

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Scientists say they may have discovered why stress makes hair turn white, and a potential way of stopping it happening without reaching for the dye.

In experiments on mice, stem cells that control skin and hair colour became damaged after intense stress.

In a chance finding, dark-furred mice turned completely white within weeks.

The US and Brazilian researchers said this avenue was worth exploring further to develop a drug that prevents hair colour loss from ageing.

Men and women can go grey any time from their mid-30s, with the timing of parental hair colour change giving most of the clues on when.

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Já ouviu aquela história de que cabelo branco muito cedo é por conta do estresse? Estudo publicado pela Harvard University revela uma ligação entre o sistema nervoso e as células-tronco que regeneram pigmentos nos folículos capilares. Leer Más

Hyper-Long Telomeres Give Non-Genetically Modified Mice Longer, Healthier Lives

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Scientists at the Spanish National Cancer Research Centre (CNIO) generated the first mice that have super-long telomeres in every one of their body cells. Studies with the animals showed that in comparison with mice that have normal length telomeres, the hyper-long telomere animals lived on average nearly 13% longer, were leaner with less white fat tissue, and had better metabolic health. The researchers generated the mice from embryonic stem (ES) cells that carry the hyper-long telomeric repeats capping the ends of their chromosomes. The most relevant achievement for the scientists is that for the first time longevity was significantly increased without any genetic modification. “This finding supports the idea that, when it comes to determining longevity, genes are not the only thing to consider,” commented research lead Maria Blasco, PhD, head of the CNIO Telomeres and Telomerase Group. “There is a margin for extending life without altering the genes.”

Blasco and colleagues published their findings in Nature Communications, in a paper titled, “Mice with hyper-long telomeres show less metabolic aging and longer lifespans.”

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Dancing can reverse the signs of aging in the brain

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As we grow older we suffer a decline in mental and physical fitness, which can be made worse by conditions like Alzheimer’s disease. A new study, published in the open-access journal Frontiers in Human Neuroscience, shows that older people who routinely partake in physical exercise can reverse the signs of aging in the brain, and dancing has the most profound effect.

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Como o exercício – em especial o treino intervalado – ajuda a mitocôndria a afastar o envelhecimento

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É frequentemente repetido, mas é verdade: o exercício mantém você saudável. Ele aumenta o seu sistema imunológico, mantém a mente afiada, ajuda a dormir, mantém o seu tônus ​​muscular e estende a sua vida saudável. Pesquisadores há muito suspeitam que os benefícios do exercício se estendem até o nível celular, mas sabem relativamente pouco sobre quais exercícios ajudam as células a reconstruir organelas-chaves que se deterioram com o envelhecimento. Um estudo publicado em 7 de março em Cell Metabolism descobriu que o exercício – e em particular o treinamento intervalado aeróbico de alta intensidade, como ciclismo e caminhada – impulsiona células a produzirem mais proteínas para suas mitocôndrias (produtoras de energia) e seus ribossomos (produtores de proteínas), efetivamente parando o envelhecimento no nível celular.

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