Caffeine coud reduce oxidative stress, improve oxygen-induced lung injury

A new study finds caffeine may protect the lungs from damage caused by prolonged oxygen therapy, such as oxygen supplementation given to premature babies.

The article is the first of its kind to study the positive effects of caffeine on the lungs’ minute tissue structures.

It is published ahead of print in the American Journal of Physiology-Lung Cellular and Molecular Physiology.

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Caffeine may counter age-related inflammation

A chronic inflammatory process that occurs in some, but not all, older people may trigger cardiovascular problems, a new Stanford study shows. Part of the solution might be found in a cup of coffee.

JAN 16,2017

Man standing in front of kids on a swing set

Mark Davis and his colleagues studied blood samples and a variety of data from more than 100 clinical trial participants and found a link between chronic inflammation and the chronic diseases that accompany aging.
Steve Fisch

Stanford University School of Medicine scientists have unearthed a connection between advancing age, systemic inflammation, cardiovascular disease and caffeine consumption.

Extensive analysis of blood samples, survey data and medical and family histories obtained from more than 100 human participants in a multiyear study has revealed a fundamental inflammatory mechanism associated with human aging and the chronic diseases that come with it.

The study, published online Jan. 16 in Nature Medicine, implicates this inflammatory process as a driver of cardiovascular disease and increased rates of mortality overall. Metabolites, or breakdown products, of nucleic acids — the molecules that serve as building blocks for our genes — circulating in the blood can trigger this inflammatory process, the study found.

The study also provides evidence that caffeine and its own metabolites may counter the action of these circulating nucleic-acid metabolites, possibly explaining why coffee drinkers tend to live longer than abstainers.

 

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