Sucrose intake lowers μ-opioid and dopamine D2/3 receptor availability in porcine brain

Average voxel-wise non-displaceable binding potential (BPND) maps superimposed on MRI images in sagittal view. Data are presented for [11C]carfentanil BPND of the 5 minipigs imaged at baseline, after initial exposure to sucrose and after 12 days of sucrose exposure (top row). [11C]carfentanil BPND of all 7 minipigs imaged at baseline and after 12 days of sucrose access are presented in the middle row. [11C]raclopride BPND of all 7 minipigs imaged at baseline and after 12 days of sucrose access are shown in the bottom row. Note that the color scale is exponential to highlight the [11C]raclopride BPND in extrastriatal regions.

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Researchers unlock mechanisms in brain that separate food consumption from cravings

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Researchers investigating eating disorders often study chemical and neurological functions in the brain to discover clues to overeating. Understanding non-homeostatic eating — or eating that is driven more by palatability, habit and food cues — and how it works in the brain may help neuroscientists determine how to control cravings, maintain healthier weights and promote healthier lifestyles. Leer Más