Common class of drugs linked to increased risk of Alzheimer’s disease

A team of scientists, led by researchers at University of California San Diego School of Medicine, report that a class of drugs used for a broad array of conditions, from allergies and colds to hypertension and urinary incontinence, may be associated with an increased risk of cognitive decline, particularly in older adults at greater risk for Alzheimer’s disease (AD).

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Estudo encontra ligação entre o pessimismo e a demência

Autores do estudo consideram que o pensamento negativo deve ser considerado um fator de risco para a doença.

Se é uma pessoa pessimista, saiba que isso não é bom para o seu cérebro. Um novo estudo descobriu que o pensamento negativo repetitivo pode estar ligado, mais tarde na vida, ao declínio cognitivo e a maiores depósitos de duas proteínas nocivas, responsáveis pela doença de Alzheimer.

«Propomos que o pensamento negativo e repetitivo possa ser considerado um novo fator de risco para a demência», afirmou a psiquiatra e autora principal do estudo,  Natalie Marchant, à CNN.

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Exercise improves memory, boosts blood flow to brain


Scientists have collected plenty of evidence linking exercise to brain health, with some research suggesting fitness may even improve memory. But what happens during exercise to trigger these benefits? New UT Southwestern research that mapped brain changes after one year of aerobic workouts has uncovered a potentially critical process: Exercise boosts blood flow into two key regions of the brain associated with memory. Notably, the study showed this blood flow can help even older people with memory issues improve cognition, a finding that scientists say could guide future Alzheimer’s disease research.

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Alzheimer: cientistas diminuem inflamação no cérebro e revertem demência

Cientistas dizem que, pela primeira vez, conseguiram reverter a demência em ratos reduzindo a inflamação no cérebro, em vez de atacar as proteínas invasoras típicas que provocam o problema, as chamadas as placas amilóides encontradas em pessoas com doença de Alzheimer.

O último estudo publicado na Science Translational Medicine sugere que o direcionamento da inflamação no cérebro pode deter a demência.

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Scientists ‘Clear’ Alzheimer’s Plaque From Mice Using Only Light And Sound

Clumps of harmful proteins that interfere with brain functions have been partially cleared in mice using nothing but light and sound.

Research led by MIT has found strobe lights and a low pitched buzz can be used to recreate brain waves lost in the disease, which in turn remove plaque and improve cognitive function in mice engineered to display Alzheimer’s-like behaviour.

It’s a little like using light and sound to trigger their own brain waves to help fight the disease.

This technique hasn’t been clinically trialled in humans as yet, so it’s too soon to get excited – brain waves are known to work differently in humans and mice.

But, if replicated, these early results hint at a possible cheap and drug-free way to treat the common form of dementia.

So how does it work?

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