Nutrient in mother’s diet may help fight Alzheimer’s in offspring

Recent research suggests that a maternal diet that is high in an essential nutrient can reduce the impact of Alzheimer’s disease on future generations.

In the study, scientists bred mice that were genetically predisposed to develop hallmarks of Alzheimer’s disease from females whose diet contained added choline.

The descendants of these females developed fewer disease-associated brain changes and had improved memory skills compared with those of non-supplemented mice.

The researchers, who are from Arizona State University (ASU) in Tempe and the Translational Genomics Research Institute in Phoenix, AZ, bred two generations of mice from the choline-supplemented females.

They found that the protective effect of “maternal choline supplementation” persisted across multiple generations, even though the descendants’ diets were not enriched with choline.

The journal Molecular Psychiatry has now published a paper on the study.

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