Nerve finding unravels mystery about communication between the gut and brain

Scientists at Flinders University have, for the first time, identified a specific type of sensory nerve ending in the gut and how these may ‘talk’ to the spinal cord, communicating pain or discomfort to the brain.

This discovery is set to inform the development of new medications to treat problems associated with gut-to-brain communication, paving the way for targeted treatments to mitigate related dysfunction.

While our understanding of the gut’s neurosensory abilities has grown rapidly in recent years, two of the great mysteries have been where and how the different types of sensory nerve endings in the gut lie, and how they are activated.

An important step in answering these questions has been made possible through the development of new techniques by Professor Nick Spencer’s Visceral Neurophysiology laboratory at Flinders University in South Australia.

Leer Más


Acetylcholine Supplements: Benefits, Side Effects, and Types

In recent years, nootropics, also called smart drugs, have gained popularity among people looking to improve their mental performance.

Acetylcholine is a neurotransmitter, or brain chemical, that plays a role in many key aspects of brain function, such as memory, thinking, and learning.

While acetylcholine supplements don’t exist, supplements that may indirectly raise acetylcholine levels have become popular among people interested in nootropics as a way to enhance mental performance.

This article explores the benefits and side effects of acetylcholine supplements, and outlines the best types.

Leer Más



Coronavirus Updates

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

– Tuberculosis Vaccine: https://bit.ly/2UFjnkd
– Experimental Peptide: https://bit.ly/2WOc3Fz
– Mask Decontamination: https://bit.ly/3dt4Z7g
– Cheap Ventilators: https://bit.ly/39ppazQ
– Swiss Survivor: https://reut.rs/2xsURuL
– Italy: https://bbc.in/2QOCUgU
– Spain: https://bit.ly/3dFynHN
– Air Pollution: https://reut.rs/3byQ7SW
– Worldwide: https://bit.ly/34228hz


Sucrose intake lowers μ-opioid and dopamine D2/3 receptor availability in porcine brain

Average voxel-wise non-displaceable binding potential (BPND) maps superimposed on MRI images in sagittal view. Data are presented for [11C]carfentanil BPND of the 5 minipigs imaged at baseline, after initial exposure to sucrose and after 12 days of sucrose exposure (top row). [11C]carfentanil BPND of all 7 minipigs imaged at baseline and after 12 days of sucrose access are presented in the middle row. [11C]raclopride BPND of all 7 minipigs imaged at baseline and after 12 days of sucrose access are shown in the bottom row. Note that the color scale is exponential to highlight the [11C]raclopride BPND in extrastriatal regions.

Leer Más



Croador

P: Si, como dices, los rituales son ejercicios fosilizados, y que la literatura o las prácticas sobreviven a su utilidad, ¿cómo explicas el por qué tanta gente las mantienen tan tenazmente? Seguramente deben de cumplir una función valiosa…

R: Que la gente quiera algo no significa que esa cosa sea buena para ellos, o incluso que esté cumpliendo una función de hecho útil o irremplazable.

Hay una historia acerca de esto, la cual ha resultado ser un remedio muy bueno contra el intento de extraer algo útil de algo inútil, o incluso dañino.

Había una vez un pueblerino que fue a un tenderete de comida para comprar un trozo de pan con berro dentro, que vendía un campesino. Apenas puso el pan en su boca, una rana saltó fuera y se acuclilló en el suelo. El pueblerino, que nunca antes había visto una rana, se agachó y la agarró. La rana croó: “¡Ghar-ghar!”.

“Con Ghar o sin ghar”, dijo el individuo, “tú vuelves dentro del pan. Al fin y al cabo, ¡pagué buen dinero por ti!”.

El buscador de la verdad